Objective　To explore the role of team-based learning （TBL） in the teaching of pe-riodontics for undergraduates. Methods　Totally 38 2008 grade undergraduates majored in stomatology were divided into six groups according to previous test scores. Individual test， group test and group re-sponder were conducted successively. Average test scores before and intra class were calculated and questionnaires survey was conducted after the course. Results　There was no significant correlation be-tween average test scores intra class and basic knowledge and preview effect（r=0.028，P＞0.05）. Ques-tionnaire survey demonstrated that learning motivation， learning interests， knowledge mastering and com-munication ability of students were significantly improved. Conclusion　TBL teaching promotes the class-room atmosphere and improves team collaboration and learning enthusiasm. Students show high accep-tance for this new teaching modes， so it can be tried in the teaching of stomatology.