Objective　To improve the teaching quality of medical genetics. Methods　A medi-cal genetics questionnaire survey was designed and conducted among 2012 grade undergraduates of Kunming Medical University. The results of the questionnaire were statistically analyzed by Kruskal-wallis test. Results　The students felt that， there were differences in the importance and difficulty of teaching sections （Z=395.818，Z=117.786，P<0.001）. The practical abilities were different after learn-ing（Z=139.364，P<0.001）. Most of the students had strong demand for clinical practice and genetic counseling， there were differences in the degree of demand in students of different majors （Z=8.432，P=0.038）. Conclusion　Method of adjusting teaching content and method was proposed and adding clinical practice in the future was recommend to improve the teaching quality .