Discussion teaching mode was carried out in the teaching of histology and embryol-ogy for clinical medical undergraduates in Chongqing Medical University from aspects of proposing questions， group learning， class discussing and summarizing. Classroom tests were accompanied to evaluate the teaching effect. It showed the discussion teaching achieved satisfactory effects. The correct answer rate of 92.36% students was ≥ 60%. Students not only acquired knowledge but also increased their comprehensive abilities. The well-supervised topics， active participation of students and timely summary of teachers at the end of the class were the key factors in the practice of the discussion teaching mode.