According to the characteristics of Introduction to Clinical Medicine and the teach ing requirements for medical English major， scaffolding instruction was introduced. The teaching method was adopted in which the key points of the whole chapter was reviewed by the students before class， the frames was built by the teacher in class and filled by the students through group discussion after class， and finally the problems which came across by the students during group discussion after class was solved by the interaction between the teacher and students in the next class. Besides， build ing tertiary grade frames made the students first understand the key points of the whole chapter verti cally and then command the progressive mechanism of every disease from basic medicine to clinical medicine and finally build the connections between the knowledge points horizontally， which inspired students' learning interest and improved their comprehensive ability to analyze the clinical case. The result proved that scaffolding instruction could improve the grades of final examination obviously and enhance the classroom efficiency.