Objective　To explore and evaluate the effects of participatory teaching approach in the teaching of medical research methods. Methods　The students of clinical medicine of Grade 2007 who took the elective course of medical scientific research method were taken as traditional teaching group

taught by teachers only

while the students of clinical medicine of Grade 2008 and 2009 as participatory teaching group

adopting the way of teachers' lectures and students' participation. At the end of the course

the questionnaire survey method combining interviews was used to investigate the teaching effectiveness

using descriptive analysis and chi-square test to compare the effectiveness between the traditional teaching methods and the participatory teaching methods. Results　Compared with the traditional 'teachers centered' method

the 'participatory teaching approach' had better teach-ing results. Through the study of this course

54 students (42.9%) learned how to conduct scientific research topics

44 students (34.9%) mastered the design of the questionnaire

59 students （46.8%） enhanced their ability of data analysis. Students' learning motivation and satisfaction were higher

and 117 student's participation （92.8%） were satisfied with the curriculum setting. Conclusion　In medical research method teaching

the effect of participatory teaching method teaching is superior to the tradi-tional teaching method

and students' motivation and satisfaction are higher.