Objective　To explore the role of state-level continuing education courses of oper-ation-room nursing in improving the nursing safety cognition in nursing staff. Methods　The state-level continuing education programs about the operating room safety and quality management were held for five sessions from Jan 2007 to Dec 2012， in which a total of 641 people participated. All participants were examined before and after each training session. The scores of the examination were utilized to evaluate the cognitive level of the operation-room nusring safety. Results　Compared with before training， the students' scores after training were significantly elevated（P<0.05）； compared with that after one training session， the students' scores after four and five training sessions were markedly increased（P<0.05）. After hospitals sending representatives to participate in the training， their operat-ing room adverse events were decreasing. Conclusion　Holding the state-level continuing education programs about operating room safety and quality management helps the nurse staff improve the cogni-tive level of operation-room nursing safety， and their cognitive level can be reinforced after receiving repeated training sessions. Moreover， holding the continuing education programs can decrease the in-cidence of adverse events and the complications in the operation-room.