The Guidelines of College English Teaching that will be issued by the Ministry of Education proposes that universities should make full use of information technology and establish multiple learning environment model based on mixed- teaching both online and offline. Medical English as an important direction of college English teaching is responded to the reform. This paper taking medical English as an example attempts to explore a new form of MOOC based on Wechat platform. It is introduced into class which is online and offline model. This teaching reform practice shows good results