Objective Discussing the application form

method and effect of Blending Learning based on MOOC in Obstetrics and Gynecology Nursing Course

in order to improve learning quality and comprehensive quality of students. Methods Randomly selected nursing undergraduate 1 class for experimental group (n=190)

another 1 for control group (n=189)

and respectively adopted Blending Learning and traditional teaching model. T test and χ2 test were adopted to compare the scores in final exam of two groups

and using Rating Scale of Self-directed Learning Competence for Nurses and the clinical communication competence scale of the nursing students in the course of the semester before and after to evaluate two groups. Results The examination result (76.30±7.08) points and excellent rate (35.79%) of test group were higher than control group (74.78±7.18) points and 25.93%

there were significance differences (P<0.05); Surveys showed that after course of test group

the autonomous learning ability and the clinical communication ability were better than before

and better than control group. Conclusion Blending Learning can apply to Obstetrics and Gynecology Nursing Course

which can effectively improve learning quality and enhance students' ability of independent study and clinical communication

the teaching effect is satisfactory to both teachers and students.