[Abstract] Objective To investigate the effect and feasibility of problem-based learning teaching model in case discussion under primary hospital and infect to practical ability of medical students. Methods Medical trainees who were organized by science and teaching department with PBL model in case discussion were as observation group and traditional case discussion by clinical departments as control group. Questionnaire survey was filled and effects between two groups were compared. Results In the cognitive domain and affective domain

PBL teaching group scored higher compared with traditional teaching group (P=0.00?0.05). Conclusion In the present environment carrying out PBL teaching model has certain feasibility and practical significance in the primary hospital and is suitable for the development trend of medical college-hospital cooperation.