Objective　To analyze the effect of flipped class mode based on grouping in pathology teaching. Method　To select four classes of clinical medical undergraduates as the objects of the study

and divide them into control group and experimental group randomly. Flipped class mode was used in con-trol group (60 people)

and flipped class mode based on grouping was used in experimental group (60 peo-ple). The effect of teaching was evaluated by test results and e-questionnaire results. The data were collated after the entry of SPSS 20.0

and the data comparison between groups was performed by t test. Result Test results and e-questionnaire results of the experimental group (28.1±0.7) were much better than those of the control group (27.5±0.9)

and the difference was statistically significant (P=0.008). It improved the learning interest

self-confidence

team spirit and ability to analyze and solve problems of the students in the experi－mental group. Conclusion　Flipped class mode based on grouping can improve the teaching quality and the self-confidence and team spirit of the students at the same time

and can lay a solid foundation for the clinical work in the future.