Objective Discuss the application effect of flipped classroom based on We-Chat and micro-course in medical chemistry experiment course in the context of internet. Methods The classes were randomly divided into 2 groups respectively

experimental group (flipped classroom teaching mode

n = 97) and the control group (traditional teaching mode

n = 98). The chemistry experiment test results of two teaching groups were compared at the end of the semester to evaluate the experimental teaching method. SPSS 12.0 software was used for statistical processing and analysis. Compare the two groups using t test. Results The chemistry experiment test score of the experimental group was higher than that of the control group [(77.84 8.22) vs (73.43 10.14)

t=3.341

p=0.008)

and the difference was statistically significant. The results of the questionnaire show that the students in the experimental group generally consider that flipped classroom teaching is better than the traditional teaching in terms of the cultivation of comprehensive quality and the teaching effect. Conclusion In the context of internet

the flipped classroom using We Chat - Micro Courses in medical chemistry experiment course can arouse the enthusiasm of students to learn and participate in better

which is popular with the students. The reformation received good results and has a good application prospect.