Objective To explore the reliability and validity of mini-clinical evaluation exercise (Mini-CEX) in neurology education during student-teacher interactive procedures. Methods 84 eight-year interns of clinical medicine and 5 teachers were assessed by Mini-CEX after teaching rounds. We calculated Chronbach's α as index of reliability for all teachers and students. Additionally

the Spearman correlation coefficients between students' performance and score of Mini-CEX were assessed as validation. Results According to the Mini-CEX table

the Chronbach's α for all teachers' evaluation was 0.986

and 0.968 for all interns. Each item in Mini-CEX was positively related with final performance of students (correlation coefficients>0.75

P<0.05). Conclusion Mini-CEX was used to evaluate both teachers and students in clinical teaching of neurology

during which it was found that Mini-CEX had good reliability and validity

and was helpful to improve the quality of clinical teaching.