Objective　To evaluate the application of Web problem-based learning (WPBL) mode of respiratory system integration curriculum. Methods　Experimentclasses 1 and 2 of the 2014 grades of the Qiqihar Medical University were divided into control group(48 students) and experiment group (48 students). Traditional PBL teaching was conducted in control group: the contents of the case were printed and discussed with the material of each class. WPBL teaching was conducted in experiment group: autonomous learning before class

showing cases by Video

asking questions and discussion in group and reporting results in class. The teaching effect was evaluated by PBL evaluation form

questionnaire and final grade. SSPS 19.0 statis-tical software was used for data analysis and measurement. T test was conducted among groups. Counting data were tested by Chi-square and the results were expressed as percentage. Results　The students in the experiment group were better than those of control groupin the aspects of contents understanding

course interest

clinical thinking ability

classroom atmosphere and the course attitude. The scores of PBL (16.65±2.82)

experiment exam (8.21±0.44) and final grade(76.77±12.31) in the experiment group were higher than those in the control group. There are statistical differences in two groups (P＜0.05). Conclusions　WPBL teaching can improve students'learning interest

clinical thinking ability and improve the teaching quality of respiratory integration curriculum.