Objective　To explore the effectiveness of the new clinical teaching method based on problem leading-in and the reform of clinical talents training mode. Methods　180 clinical interns in de-partment of urology were selected as the subjects

which were randomly divided into experimental group and control group (90 clinical interns in each group). The clinical teaching effects of the two groups were compared by adopting the new clinical teaching methods and the traditional ones. Evaluation indexes con-sists of theoretical scores

operational skills and personal comprehensive quality scores. Results　 The results of the above three tests in the experimental group were all superior to those of the control group (P<0.05). The satisfaction of the experimental group in teaching method

teaching effect and teacher evaluation was obviously better than that in the control group (P<0.05). Conclusion　The implementation of the new clinical teaching method based on problem leading-in is not only beneficial to improve the knowledge skills

com-prehensive quality and teaching satisfaction of clinical medical students

but also to the training of clinicians with high quality. The new clinical teaching method is of great significance for reforming the mode of clini-cal medical talents.