Objective　To evaluate the application effect of mini-clinical evaluation exercise (Mini-CEX) in the clinical teaching of orthopedics. Methods　A total of 60 students who finished their orthopedics internship in Renji Hospital of Shanghai Jiao Tong University from January 2017 to July 2017 were in-volved and randomly divided into the experimental group and the control group with 30 students in each group. The experimental group received Mini-CEX while the control group received traditional lessons. Sur-veys and tests were conducted after the internship and the results were recorded. All statistical analyses were performed with the independent sample t test and Chi-square test using SPSS software (version 21.0). Results　Except for communication skills

the medical counseling skills

physical examination skills

humanistic qualities

clinical diagnosis

organization and overall clinical competence were higher in the experimental group than in the control group and the difference was statistically significant (P<0.05). The improvements in clinical diagnosis ( χ2=6.674

P=0.036)

professional knowledge and skills ( χ2=6.455

P=0.040)

clinical practice skills ( χ2=6.673

P=0.036) and satisfaction ( χ2=6.881

P=0.032) were greater in the experimental group than in the control group and the difference was statistically significant (P<0.05). No significant difference was observed in the inspiration of learning interest( χ2=4.025

P=0.134) and the improve-ments in language proficiency ( χ2=4.993

P=0.085)

medical history acquisition ability ( χ2=1.564

P=0.458)

humanistic qualities ( χ2=2.982

P=0.255) and teamwork ( χ2=2.651

P=0.266) between the two groups. Conclusion　Mini-CEX not only achieves higher satisfaction but also helps students to improve their pro-fessional knowledge and skills

clinical diagnosis and clinical practice skills. Besides

Mini-CEX in the clinical teaching of orthopedics can effectively improve the quality of teaching and the satisfaction of students

thus providing a new teaching mode worthy of popularization.