Objective To explore the effects of “2+1” PAD Class on “medical statistics” teaching by applying online learning

classroom instructing and classroom seminar. Method quasi experiment method was conducted in this study. 186 students taught by “2+1” method were recruited from four classes of clinical medicine for experiment group

140 students were selected into control group

using traditional teaching method. The feedback from students of two groups about the teaching progress and effects would be compared in this study. Result the students claimed that the “2+1” teaching method paid more attention on discipline crossing than traditional method (P<0.001)

and the new method brought more benefits for capacity training (P=0.008)

research technique learning (P=0.012)

comprehensive satisfaction scores (P<0.001) and comprehensive problems solving (P<0.001). Conclusion Based on online courses

the “2+1” pad class teaching model has more advantages than traditional teaching methods. Therefore

this method is deserved to be implemented and recommended in college teaching.