Objective　To explore the application of 3D printing technology combined with CPBL teaching mode in the teaching of master's degree in spine surgery. Methods　42 postgraduates in our department were randomly divided into two groups: experimental group (21) and control group (21). The experimental group used 3D printing technology combined with CPBL teaching mode as teaching techniques. Before class， the teacher would select some typical cases and design related problems. During class

3D models were used to guide students to think and solve related problems; The control group used traditional teaching mode. Students in the two groups were compared for the theoretical knowledge and operational techniques they have mastered

and the students' satisfaction and recognition towards different teaching modes were obtained through questionnaire survey. Independent sample t-test was performed using SPSS 25.0. Results　The scores of the theoretical knowledge

operational techniques

teaching satisfaction and recognition of postgraduates were (84.7±3.4)

(87.1±3.7)

(9.7±0.3)

(9.3±0.4) in the experimental group

and (79.7±3.3)

(80.4 ± 4.0)

(8.4±0.7) and (8.3±0.6) in the control group. The difference between the two groups was statistically significant (P<0.05). Conclusion　The new teaching mode of combining 3D printing technology with CPBL teaching mode is better than the traditional teaching mode

which is worth further promotion and application.