Objective　To introduce the application of 3D printing technology in standardized residency training of percutaneous precise biopsy. Methods　Twenty-two residents were randomly divided into innovative teaching group and traditional teaching group

with 11 ones in each group. Residents in both groups received standardized training of percutaneous biopsy procedure. Innovative teaching group was given 3D printing template combined with guided operation

while traditional teaching group used bare hand operation. The time spent in biopsy

the times of needle adjustment

the frequency of CT scanning during operation

the positive rate of material sampling and the incidence of complications were compared between the two groups. Results　During the percutaneous lung biopsy

two groups of physicians performed the procedure. There was no significant difference between the two groups in operation time [(22.34±3.12) vs. (23.56±4.21)] and the positive rate of sampling (72.73% vs. 90.91%) (P > 0.05)

but there were significant differences in the times of adjusting biopsy needle during operation [(2.11±0.67) vs. (1.02±0.93)]

the frequency of intraoperative CT scanning [(4.35±0.76) vs. (3.12±0.84)] and the incidence of complications (54.55% vs. 27.27%) (P < 0.05). In percutaneous peritoneal organ biopsy

there was no significant difference among the two groups in the operation time [(16.25±2.89) vs. (15.12±2.59)]

the number of CT scans [(3.45±0.79) vs. (2.98±0.23)] and the positive rate (78.57% vs. 88.24%) (P > 0.05)

but there were significant differences in times of intraoperative biopsy needle adjustments [(2.43±0.43) vs. (1.84±0.89)] and the incidence of complications (35.71% vs. 5.88%) (P < 0.05). Conclusion　The application of 3D printing technology combined with the teaching of three-dimensional guided stent can make percutaneous biopsy technique stylized and standardized. It is of great significance to standardize the operation for improving the quality of medical treatment

and it is worth popularizing in clinical teaching.