Objective　To study the effect of micro-course teaching combined with teacher standardized patient combined with objective structured clinical examination (TSP/OSCE) on clinical practice teaching of pediatric nursing. Methods　Forty nurses who performed clinical practice in Pediatrics Department from February 2019 to July 2019 were selected as the control group

and traditional teaching was adopted in the group. In addition

42 nurses who performed clinical practice in Pediatrics Department from August 2019 to January 2020 were selected as the research group

and the micro-course teaching combined with TSP/OSCE mode teaching was adopted in the group. Two groups of nurses' theoretical and practical skills assessment results were analyzed

and a questionnaire survey was conducted to assess nurses' satisfaction with the teaching of pediatric nursing clinical practice training mode. SPSS 22.0 was used for t test and chi-square test. Results　The research group nurses' theoretical and practical skills assessment scores were better than those of the control group

and the difference was statistically significant (P=0.000). The nurses in the research group were more satisfied than those in the control group with such eight aspects as improving practical skills

emergency response capabilities

humanistic care and service capabilities

communication skills

and stimulating their interest in nursing learning. There were statistically significant differences (P<0.05). Conclusion　The use of micro-teaching combined with TSP/OSCE mode in the clinical practice teaching of pediatric nursing can improve nurses' clinical practice ability and increase nurses' satisfaction in pediatric training.