Objective　To explore the application effect of flipped classroom combined with simulated case teaching in internship of pediatric nursing students. Methods　In the study

52 nursing interns having internship in our department from July 2018 to January 2020 were selected and divided into control group and experimental group according to the internship period

including 26 interns in each group. The control group adopted traditional teaching method

while the experimental group adopted flipped classroom teaching method combined with simulated case drill. Indicators such as assessment scores and satisfaction surveys were compared between the two groups. Results　Compared with the control group

the test results of nursing students in the experimental group [(77.077±5.455) points] were significantly better than those [(67.692±4.905) points] in the control group (P<0.01). The teaching satisfaction of nursing students in the experimental group (99.78%) was significantly better than that (89.92%) in the control group (P<0.01). Conclusion　The application of flipped classroom combined with simulated case practice teaching method in the internship teaching of pediatric nursing students has achieved good results

which is worthy of promotion in the teaching of pediatric nursing drill.