Objective　To explore the application effect of flipped classroom teaching combined with micro-classes and PBL in the training of refresher nurses. Methods　Using the cluster sampling method

35 refresher nurses from March 2017 to February 2018 were collected as the control group

and 38 refresher nurses from March 2018 to February 2019 were included as the observation group. The control group received the theoretical knowledge training of respiratory specialty by traditional teaching method

and the observation group received theoretical knowledge training of respiratory specialty by using flipped classroom teaching combining micro-classes and PBL. Before and after the training

the special theory assessment with the same difficulty was carried out

and the clinical teaching evaluation was carried out after the training. Results　After the training

the special theory assessment scores of the observation group were significantly higher than those of the control group (t=7.560

P<0.05)

with significant differences. Compared with the control group

the clinical teaching evaluation scores of the nurses in the observation group were significantly improved (t=24.657

P<0.05)

with significant differences

especially in the nurses' learning attitude

learning ability

teaching style and teaching satisfaction scores. Conclusion　The flipped classroom teaching combining micro-classes and PBL can significantly improve the special theory assessment scores of refresher nurses

promote the internalization of specialized knowledge

turn to active learning from the passive mode

change the learning attitude of refresher nurses

improve their recognition of clinical teachers and realize teaching benefits as well as learning benefits.