In order to discuss the role and significance of the three-dimensional portable document format(3D PDF) in the learning of cerebrovascular disease

this study created 3D PDF of complex cerebrovascular disease models to aid the teaching of cerebrovascular disease. The cerebral blood vessels

skull and brain tissue were segmented using the CTA image of the patient's brain. Then the 3D models were reconstructed

smoothed

and simplified. Based on this

Deep Exploration and Acrobat software were used to integrate these models into a 3D PDF file

which was used as an auxiliary tool for the teaching of cerebrovascular diseases for medical undergraduates. Finally

the feedback information of questionnaires was collected and analyzed statistically. The questionnaire results showed that the students have a strong interest in interactive 3D PDF. They believe that 3D PDF is more visual and intuitive than 2D CT or MRI images

and greatly agree with the positive effects of 3D PDF in the teaching of cerebrovascular disease and in clinical application.