Objective　To explore the effect of situational simulation training combined with Miller pyramid teaching on emergency response ability and nursing skills of specialized nurses in operating room. Methods　A total of 56 disaster nursing trainees who received specialized nurse training in the operating room of Mianyang Central Hospital from June 2019 to June 2020 were selected in the study

and they were divided into control group and research group in average according to the order of training time. The control group adopted clinical one-to-one teaching

while the research group adopted situational simulation training combined with Miller pyramid teaching. After the training

the teaching effect of specialized nurse training was evaluated by their professional theoretical knowledge and nursing skill operation results

and self-designed assessment scale was used to evaluate the emergency response ability and satisfaction with the training effect of the nurses. SPSS 22.0 was used for t test and chi-square test. Results　The results of theoretical knowledge and nursing skills operation of specialize nurses in operating room in the research group were significantly higher than those in the control group

and the differences were statistically significant (P<0.001). The scores of emergency capability assessment in the research group were significantly higher than those in the control group

with statistical significance (P<0.001). The study group was better than the control group in 7 aspects of satisfaction

such as the improvement of the operation level of emergency ability

team cooperation ability

analysis and problem solving ability

clinical nursing decision-making ability

independent thinking ability and nurse-patient communication ability

with significant differences (P<0.05). Conclusion　Situational simulation training combined with Miller pyramid teaching can significantly improve the emergency response ability

nursing skill operation and training satisfaction of operating room nurses

which is better than the traditional clinical teaching method

and is worthy of application and promotion in clinical nursing teaching.