微囊包膜纯化初生猪胰岛移植治疗糖尿病大鼠研究

舒昌达; 李佐强; 何军

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微囊包膜纯化初生猪胰岛移植治疗糖尿病大鼠研究

更新时间：2024-01-17

- 微囊包膜纯化初生猪胰岛移植治疗糖尿病大鼠研究
- SUCCESSFUL MICROENCAPSULATED PURIFIED NEONATAL PORCINE ISLETS TRANSPLANT FOR THE TREATMENT OF DIABETIC RATS
- 重庆医科大学学报 1994年第3期
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  中图分类号： R657.5
- 纸质出版日期：1994，
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[1]舒昌达,李佐强,何军.微囊包膜纯化初生猪胰岛移植治疗糖尿病大鼠研究[J].重庆医科大学学报,1994(03):185-186+191.

SUCCESSFUL MICROENCAPSULATED PURIFIED NEONATAL PORCINE ISLETS TRANSPLANT FOR THE TREATMENT OF DIABETIC RATS[J]. Journal of Chongqing Medical University, 1994,(3).
[1]舒昌达,李佐强,何军.微囊包膜纯化初生猪胰岛移植治疗糖尿病大鼠研究[J].重庆医科大学学报,1994(03):185-186+191. DOI：

SUCCESSFUL MICROENCAPSULATED PURIFIED NEONATAL PORCINE ISLETS TRANSPLANT FOR THE TREATMENT OF DIABETIC RATS[J]. Journal of Chongqing Medical University, 1994,(3). DOI：

摘要

在链脲佐菌素所致的８只糖尿病Ｗｉｓｔａｒ大鼠腹腔内移值免疫隔离膜包囊纯化初生猪胰岛，观察效果。移值后有效率为８８％，完全援解率为５０％，且缓解持续时间最长一只达１８０天以上。对照组无效。这证实我们所研制的免疫隔离包囊初生猪胰岛在异种移植过程中起到预期的抗排异反应，故可进入临床以治疗糖尿病患者。

Abstract

urified neonatal porcine islets encapsulated in the immtino-isolated membrane were transplanted in-traperitoneally into elght streptozotocin induced diabetic rats. The effective rates

88%and 50%were com-plete remission. The longest normoglycemic period in thOse rats was over 1 80 days

There was no effect incontrol group. Those prove that the immuno-isolated Tnembrane encapsulated neonatal porcine islets may notbe in jured by the rejection during xenotransplantation and is ready for clinical use in the treatment of diabetitpatients.

关键词

免疫隔离膜微囊异种胰岛移植

Keywords

Immuno-isolated membraneMicrocapsulesXenotransplantation of islets of Langer-hans

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