OBSERVATION OF THE PATHOLOGYOFCHOLESTEROL POLYP OF GALLBLADDER AND THE BIOCHEMICAL CHANGE IN BILE[J]. Journal of Chongqing Medical University, 1994,(1).
OBSERVATION OF THE PATHOLOGYOFCHOLESTEROL POLYP OF GALLBLADDER AND THE BIOCHEMICAL CHANGE IN BILE[J]. Journal of Chongqing Medical University, 1994,(1).DOI:
series of cases of cholesterol polyp of gallbladdcr were presented
and tho pathological
mucochemical and the uItrastructure changes of gallbladder observed.The Contents of cholestcro-Lphospholipid and bile acid in cystic bile were determined in thcse cases and compared with thoseof healthy persons and cascs of cholesterol stone in gallbladder.It showed that the cholesterolconcentration increased signlficantly in cases of cholesterol polyp
The oversaturated cholesterol inbilo was deposited on the mucous membrane of gallbladder
Posited cholestcrol changed phagocytesinto goam cells and stimulated the mucous membrac to profude to form cholcsterol polyp.Thephenomeon that the phagocutosis of epithelium cells of cystic mucous membrane to lipid probably isthe reaction of gallbaldder to the cholesterol edposited in bile
This phenomenon may play role inthe process of chelcsterol endosmosis. High concentration of cholesterol may be the main cause andinintial factor that damages the barrier of the mucous membrane of gallbladder and leads tocholesterol polyp formation.The multipotential mesenchymal cells perhaps are another source offoam cells.