To evaluate the diagnostic value of acute phase proteins(APPS)and EBV IgA/VCA

IgA/EA for nasopharyngeal carcinoma(NPC)

the serum APPs including sialic acid(SA)

al-antit- rypsin(a1-AT)

a1-acidyglycoproteins(a1-AGP)

Haptoglobin(HP)

Transferrin(TF)

and preal-bumin(PA)and EBV IgA/VCA

IgA/EA were determinated in 190 patients with NPC.The dis-criminatnt function equations

with wich the disriminant diagnosis for NPC was ’made

were obtamed by stepwise discriminant analysis with APPs.It was found that in pretreated NpC group the agreement rates of APPs and EBV-IgA/ VCA

IgA/EA with clinical patholgical diagnosis were 81.88 % and 56.57% respoctively

but in treated caseswithout evidence of recurrence were 80.95 % and 28.57 % respectively. Our results suggested that the APPs werebetter than EBV IgA/VCA

IgA/EA for diagnosis and follow-up of NPC.