he in-vitro activity of teicoplahin was evaluated against 165 strains of Gram-positive cocci isolated clini-cally

and was compared with 11 other antibacterial agents

The results showed tbat teicoplanin had excellentantibacterial activities against methicillin-sensitive or resistant Staphylococcus aureus

Streptococcus pneumo-niae and Streptococcus viridans. MIC9Os were≤2mg/L

and inhibition rates were 95%to 100%. Teicoplaninalso had good activity against methicillion-sensitive or resistant StaphJococcus epidermidis。But MIC 90 was64mg/L for Strepptococcus fecalis and inhibition rate was 58.3%. MIV9Os of norvancomycin against MRSA

MRSE

Streptococcus fecalis vvere 2

1. and 64mg/L. Inhibition rates were 100%

85.7%and 66.7%respec-tively