尿NAG测定对早期糖尿病肾病的诊断意义探讨

李启富; 何军; 舒昌达

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尿NAG测定对早期糖尿病肾病的诊断意义探讨

更新时间：2024-01-17

- 尿NAG测定对早期糖尿病肾病的诊断意义探讨
- URINARY N-ACETY1-β-D-GLUCOSAMIMDASE DETERMINATION FOR DETECTION OF DIABETIC NEPHROPATHY AT EARLYSTAGE
- 重庆医科大学学报 1996年第3期
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  中图分类号： R587.2
- 纸质出版日期：1996，
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[1]李启富,何军,舒昌达.尿NAG测定对早期糖尿病肾病的诊断意义探讨[J].重庆医科大学学报,1996(03):236-238.

URINARY N-ACETY1-β-D-GLUCOSAMIMDASE DETERMINATION FOR DETECTION OF DIABETIC NEPHROPATHY AT EARLYSTAGE[J]. Journal of Chongqing Medical University, 1996,(3).
[1]李启富,何军,舒昌达.尿NAG测定对早期糖尿病肾病的诊断意义探讨[J].重庆医科大学学报,1996(03):236-238. DOI：

URINARY N-ACETY1-β-D-GLUCOSAMIMDASE DETERMINATION FOR DETECTION OF DIABETIC NEPHROPATHY AT EARLYSTAGE[J]. Journal of Chongqing Medical University, 1996,(3). DOI：

摘要

测定４２例ＮＩＤＤＭ患者随意尿Ｎ—乙酰—β—Ｄ—氨基葡萄糖苷酶（ＮＡＧ）活性，与尿白蛋白（ＡＬＢ）进行对比。结果显示：（１）糖尿病Ａ组（ＡＬＢ＜５０ｍｇ／Ｌ）尿ＮＡＧ增高百分率（６６．７％），与ＡＬＢ增高百分率（７０．８％）相比，Ｐ＞０．０５，提示尿ＮＡＧ诊断早期糖尿病肾病的敏感性与ＡＬＢ相似；（２）糖尿病Ａ组患者尿ＮＡＧ和ＡＬＢ均增高者占４５．８％，仅ＮＡＧ增高者占２０．８％，仅ＡＬＢ增高者２５．０％。对糖尿病患者宜同时监测尿ＡＬＢ和ＮＡＧ。

Abstract

rinary N-acetyl-β-D-glucosaminidase activity(NAG)and urinary albumin(ALB)wereexamined in 42 patients with non-insulin-dependent diabetes mellitus.The results showed:(1)Indiabetic group A(ALB < 50mg/L)

the percentages of increased values of urinary NAG and ALBwere 66.7%and 70.8%respectively.Between them there was no significant dif-ference(P> 0.05)

which suggested that NAG was similar to ALB in sensitivity for detection ofdiabetic nephropathy at early stage;(2)In diabetic group A

11 patients(45.8%)presented a mixedelevation of both NAG and ALB

and 5 patients(20.8%)and6(25.0%)showed only an elevation ofNAG or ALB respectively. It seems that quantitation of both urinary NAG and ALB is the best wayfor scroening of early renal involvement in patients with diabetes mellitus.

关键词

糖尿病肾病尿白蛋白尿N—乙酰—β—D—氨基葡萄糖苷酶

Keywords

diabetic nephropathyUrinary albuminN-acetyl-β-D-glucosimidase

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