异丙酚全凭静脉麻醉对颅内肿瘤病人颅内压、脑灌注压的影响

陈萍; 陈敦敏; 周泽军; 蒋夏; 唐文渊; 朱继; 王波

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异丙酚全凭静脉麻醉对颅内肿瘤病人颅内压、脑灌注压的影响

更新时间：2024-01-17

- 异丙酚全凭静脉麻醉对颅内肿瘤病人颅内压、脑灌注压的影响
- The propofol total intravenous anesthesia for patientswith elevated intracranial pressure
- 重庆医科大学学报 1997年第2期
- 作者机构：
- 作者简介：
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  中图分类号： R614.2
- 纸质出版日期：1997，
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[1]陈萍,陈敦敏,周泽军,蒋夏,唐文渊,朱继,王波.异丙酚全凭静脉麻醉对颅内肿瘤病人颅内压、脑灌注压的影响[J].重庆医科大学学报,1997(02):145-147.

The propofol total intravenous anesthesia for patientswith elevated intracranial pressure[J]. Journal of Chongqing Medical University, 1997,(2).
[1]陈萍,陈敦敏,周泽军,蒋夏,唐文渊,朱继,王波.异丙酚全凭静脉麻醉对颅内肿瘤病人颅内压、脑灌注压的影响[J].重庆医科大学学报,1997(02):145-147. DOI：

The propofol total intravenous anesthesia for patientswith elevated intracranial pressure[J]. Journal of Chongqing Medical University, 1997,(2). DOI：

摘要

１４例颅内肿瘤患者，用异丙酚２ｍｇ／ｋｇ行麻醉诱导，气管插管后用０．２％异丙酚按６ｍｇ／ｋｇ／ｈ．４．５ｍｇ／ｋｇ／ｈ．３ｍｇ／ｋｇ／ｈ三步递减的速度维持麻醉，观察诱导前后及术中颅内压。平均动脉压、脑筋注压的变化。结果发现颅内压明显下降，而平均动脉压及灌注压在诱导时下降，气管插管后回升至诱导前水平，术中保持稳定。异丙酚全凭静脉麻醉非常适宜于神经外科手术。

Abstract

The effects of propofol total intravenous anesthesia on intracranial pressure(ICP)

mean arteial press-ure(MAP)and cerebral perfusion pressure(CPP)were observed in 14 patients with elevated intracranial pressurescheduled for craniotomy.Anesthesia was induced with propofol 2mg/kg and maintained with infusion of 0.2%propofol The results showed:(1)ICP decreased 18.4% and 25.4% in 2 and 4 minutes of induction;MAP decreased20% and 22.9%;CPP decreased 18.2% and 26.7% P<0.05.(2)After incubation

ICP remained lower thanpre-induction level

MAP and CPP returned to pre-induction level

(3)CPP increasedobviously when tumor wasresected.It is concluded that propofol total intravenous anesthesia is appropriated for patients with elevated ICP.

关键词

异丙酚（Propofol）颅内压（ICP）平均动脉压（MAP）脑灌注压（ICP）

Keywords

PropofolICPCPPMAP

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