异丙酚诱导、普鲁卡因静脉复合液维持麻醉对颅内压、脑灌注压的影响

陈敦敏; 陈萍; 周泽军; 唐文渊; 高晋建

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异丙酚诱导、普鲁卡因静脉复合液维持麻醉对颅内压、脑灌注压的影响

更新时间：2024-01-17

- 异丙酚诱导、普鲁卡因静脉复合液维持麻醉对颅内压、脑灌注压的影响
- The effect of induction of propofol and maintenance with procaninebalanced anesthesia on intracranial pressure, maen blood pressure andcerebral perfusion pressure
- 重庆医科大学学报 1997年第3期
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  中图分类号： R614.27
- 纸质出版日期：1997，
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[1]陈敦敏,陈萍,周泽军,唐文渊,高晋建.异丙酚诱导、普鲁卡因静脉复合液维持麻醉对颅内压、脑灌注压的影响[J].重庆医科大学学报,1997(03):217-221.

The effect of induction of propofol and maintenance with procaninebalanced anesthesia on intracranial pressure, maen blood pressure andcerebral perfusion pressure[J]. Journal of Chongqing Medical University, 1997,(3).
[1]陈敦敏,陈萍,周泽军,唐文渊,高晋建.异丙酚诱导、普鲁卡因静脉复合液维持麻醉对颅内压、脑灌注压的影响[J].重庆医科大学学报,1997(03):217-221. DOI：

The effect of induction of propofol and maintenance with procaninebalanced anesthesia on intracranial pressure, maen blood pressure andcerebral perfusion pressure[J]. Journal of Chongqing Medical University, 1997,(3). DOI：

摘要

１１例颅内压增高行硕内肿瘤切除术患者，用异丙酚２ｍｇ／ｋｇ诱导，普鲁卡因静脉复合液维持麻醉，按普鲁卡因１ｍｇ／ｋｇ／ｍｉｎ滴入。诱导前，后共３５ｍｉｎ，观察ＭＡＰ、ＩＣＰ、ＣＰＰ变化。结果发现：异丙酚可使ＩＣＰ迅速显著降低（Ｐ＜００１）；诱导开始到插管后，ＣＰＰ无显著变化（Ｐ＜０．０５），插管１０ｍｉｎ后有显著升高。结果认为：异丙酚可使高颅压患者ＩＣＰ迅速显著下降；普鲁卡因维持麻醉，可较好地维持循环功能，稳定，和维护脑的自身调节能力，对ＩＣＰ下降起到协同作用。

Abstract

Intracranial pressure (ICP)

mean blood pressure (MDP)and cerebral perfusion pressure (CPP) were measured in 11 patients with intracranial hypertension scheduled for elective cranitomy with induction of propofol 2mg/kg and maintenance with procaine balanced anesthesia (procaine infusion rate 1mg/kg/min).Continued measurement of ICP

MBP were made from the induction till 35 minutes after incubation.The results show:ICP decreases significantly from 2 minutes of the induction till 35 minutes after the incubationP<0.01;CPP have no significant change during induction but significant increase 10 minutes after incubation.The induction of propofol 2mg/kg decreases ICF of patients with intracranial hypertension.Maintenance with procaine balanced anesthesia could keep a stable circulation and brain autoregulation.Another procaine also plays a role in long time decrease of ICP.

关键词

异丙酚普鲁卡因复合麻醉ICP

Keywords

propofolProcaine balanced AnesthesiaIntracranial pressure

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