The effect of intravenous

Gelofusine on plasma tissue-type plasminogen activator)t-PA_

plasminogenactivator inhibitor(PAI)

D-Dimer and plasmin imhibitor was studied in 25 surgical patients underepidural anesthesia. Results showed that there was no significant difference of plasma levels of t-PA

PAI

D-Dimer and PI between pre-intravenous Gelofusine and immediately

2 hours and 24 hours afterintravenous Gelofusine

The conclusion was that Gelofusine didn’t influene surgical patients’ fibrinolyticfunction.