To evaluate the diagnostic value of sialic acid (SA)and acute phase proteins(APPs)for laryugeal carcinoma(LC)

the SA and APPS(Prealbumin

α 1-Antitrypsin

α 1-Acid glycoprotein

Haptoglobin.Transferrin)were determined

and the discriminant functions

by which the discriminant diagnosis was made established.The discriminant function(Ⅰ)for discriminant diagnosis of LC was derived from the data of 58 patients with LC and 58 healthy subjects

another one (Ⅱ)for follow-up after treatment from 19 patients had recurrence or metastasis and 20 tumour-free patients after cure.The discriminnt diagnosis was made with (Ⅰ)for 103 patients unknown diagnosis at the time of presentation.Comparing with histological diagnosis

the precision of discriminant diagnosis was86%

Following-up 79 patients with LC after treatment

the precision of discriminant diagnosis with (Ⅱ) to detect recurrence or metastasis was 86 1%。 In conclusion

determination of SA and APPs can used for diagnostic and prrognostic purpose.