NIDDM患者红细胞膜流动性改变与血浆胰岛素和糖化血红蛋白水平的关系

杨刚毅; 邱鸿鑫; 邓华聪; 汪恕萍; 张素华; 粟绍初; 李萍

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NIDDM患者红细胞膜流动性改变与血浆胰岛素和糖化血红蛋白水平的关系

更新时间：2024-01-17

- NIDDM患者红细胞膜流动性改变与血浆胰岛素和糖化血红蛋白水平的关系
- Erythrocyte membrane fluidity and its relationshipwith fasting plasma insulin and glycosylated hemoglobinlevels in noninsulin-dependent diabetes mellitus
- 重庆医科大学学报 1997年第2期
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  中图分类号： R587.1
- 纸质出版日期：1997，
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[1]杨刚毅,邱鸿鑫,邓华聪,汪恕萍,张素华,粟绍初,李萍.NIDDM患者红细胞膜流动性改变与血浆胰岛素和糖化血红蛋白水平的关系[J].重庆医科大学学报,1997(02):100-101.

Erythrocyte membrane fluidity and its relationshipwith fasting plasma insulin and glycosylated hemoglobinlevels in noninsulin-dependent diabetes mellitus[J]. Journal of Chongqing Medical University, 1997,(2).
[1]杨刚毅,邱鸿鑫,邓华聪,汪恕萍,张素华,粟绍初,李萍.NIDDM患者红细胞膜流动性改变与血浆胰岛素和糖化血红蛋白水平的关系[J].重庆医科大学学报,1997(02):100-101. DOI：

Erythrocyte membrane fluidity and its relationshipwith fasting plasma insulin and glycosylated hemoglobinlevels in noninsulin-dependent diabetes mellitus[J]. Journal of Chongqing Medical University, 1997,(2). DOI：

摘要

本文观察３６５例非胰岛毒依赖型糖尿病（ＮＩＤＤＭ）人红细胞膜流动性，并探讨了膜流性与空腹血浆胰岛素（ＦＰＩ）、空腹血糖（ＦＢＧ）和糖化血红蛋白（ＨｂＡ１ｃ）水平的关系．结果表明：ＮＩＤＤＭ患者红细胞膜微粘度明显高于同年龄正常对照组，提示其红细胞膜流动性降低。并且患者膜微粘度与ＦＢＧ浓度和ＨｂＡ崐１ｃ水平呈明显正相关，而与ＦＰＩ浓度呈明显负相关，上述结果说明ＮＩＤＤＭ患者红细胞膜流动性改变与病情控制有关。

Abstract

Erythrocyte membrane fluidity and its relationship with fasting plasma insulin(EPI)

fasting blood glucose(FBG)and glycosylated haemoglobin(HbA1c)levels were studied in 65 noninsulin-dependent diabetes mellitus(NIDDM)The results showed that NIDDM patients had incrased erythrocyte membranemicroviscosity2.543±0.294 in 65 NIDDM vs 2.250±0.226 poise in 29 controls

P<0.01)as compared with the age-matchedcontrol group.This result suggested a decreased erythrocyte membrane fluidity in NIDDM patients.Themicroviscosity of erythrocyte membrane from diatebic subjects was significantlycorrelated FBG(r=0.227

P<0.05)and HbA1c levels(r=0.399

P<0.01)

inversely correlated with FPI(r=-0.233

P<0.05).These results indicated that erythrocyte membrane fluidity was closely related with diabetic control inNIDDM.

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NIDDM膜流动性血浆胰岛素

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