A study was made on 93 surgical specimens of meningiomas.The specimens included 21 malignant meningiomas(MM)

25 benign meningiomas with recurrence after completely surgical removal (RBM). 12 benign meningiomas with invasion into dura

skull or muscle (IBM)and 35 simple benign meningiomas without recurrence after surgical treatment 6 or more years(SBM). Four methods were used

namely

DNA image analysis technology(IAT)

proliferating cell auclear antigen(PCNA)

Ki - S1 monoclonal antibodies immunohistochemical staining and argyrophilic nucleolar organizer regions (AgNOR) in order to study the characteristics of meningioma is cell kinetics and their values in biological behaviours.The results indicate:(1)The proliferating potential of the MM. RBM and IBM is much greater than that of the SBM(P<0.01) and the benign meningioma’s recurrence or invasion is related to its proliferating ability;(2) The DNA

PCNA

Ki - S1 and AgNOR are all useful to assess the meningioma’s proliferating potential

and are significantly related to each other(P<0.01).Among the methods

Ki - S1 is the simplest and most sensitive . AgNOR is not only sensitive but also repeatable;(3) when benign meningima’s AgNOR number per cell nucleus is 2.8 or more the meningioma is more likely to recur (P< 0. 05).