Changes of plasma adrenomedullin and adrenotensin in swimrats and LNNA-induced hypertensive rats[J]. Journal of Chongqing Medical University, 1998,(2).
Changes of plasma adrenomedullin and adrenotensin in swimrats and LNNA-induced hypertensive rats[J]. Journal of Chongqing Medical University, 1998,(2).DOI:
t was found that plasma ADM level was increased by 26%(P<0.05)and 120%(P<0.01)
plasma ADT level wasdecreased by 31%(P<0.01)and 30%(P<0.01)and plasma ADM/ADT ratio was increased by 76%(P<0.01)and200%(P<0.01)respectively in swim rats and in hypertensive rats induced by LNNA.These data suggest thatsport and pathogenesis and developmet of hypertension could lead to absolute and/or relative increase of plasmaADM by regulating production/secretion of ADM and ADT.We deduced that the changed of plasma ADM andADT be one of mechanisms of the body in resisting hypertension and also one of mechanisms of sport inprevention and treatment of hypertension.