Objective: To elucidate the clinical value of Fine Needle Aspiration Cytology (FNAC) in diagnosis of lung disease. Methods: 248 report of cases and literature were reviewed. Results: The positive rates of FNAC were greater than those of sputum and fibre broncialscope (P<0.005)
and the results of FNAC were believable in diagnosis of lung disease. To combine FNAC with biopsy can improve the rate of diagnosis. Conclusion: Those of accompanying with superficial lymph node would be done FNAC as soon as possible. The operation is simple rapid and patients have less suffering. It is valuable to popularize.