喷昔洛韦乳膏与阿昔洛韦乳膏治疗单纯疱疹临床对比观察

周汛; 李桂明; 李惠

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喷昔洛韦乳膏与阿昔洛韦乳膏治疗单纯疱疹临床对比观察

更新时间：2024-01-17

- 喷昔洛韦乳膏与阿昔洛韦乳膏治疗单纯疱疹临床对比观察
- Observation of therapeutic effects on treating herpes simplex with penciclovir cream and acyclovir cream
- 重庆医科大学学报 2001年第2期页码：181-182
- 作者机构：
  
  重庆医科大学临床学院皮肤科,重庆,400016
- 作者简介：
- 基金信息：
- DOI：
  中图分类号： R752.11
- 纸质出版日期：2001，
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[1]周汛,李桂明,李惠.喷昔洛韦乳膏与阿昔洛韦乳膏治疗单纯疱疹临床对比观察[J].重庆医科大学学报,2001(02):181-182.

Observation of therapeutic effects on treating herpes simplex with penciclovir cream and acyclovir cream[J]. Journal of Chongqing Medical University, 2001,(2):181-182.
[1]周汛,李桂明,李惠.喷昔洛韦乳膏与阿昔洛韦乳膏治疗单纯疱疹临床对比观察[J].重庆医科大学学报,2001(02):181-182. DOI：

Observation of therapeutic effects on treating herpes simplex with penciclovir cream and acyclovir cream[J]. Journal of Chongqing Medical University, 2001,(2):181-182. DOI：

摘要

目的：评价喷昔洛韦乳膏治疗单纯疱疹的疗效和安全性。方法：将64例单纯疱疹患者随机分为喷昔洛韦乳膏治疗组和阿昔洛韦乳膏对照组。治疗后第1，2，4，6，10，14天观察记录。结果：治疗组与对照组在结痂开始时间、完全结痂时间、脱痂开始时间和完全脱痂时间比较均有显著性差异（Ｐ<0.05），痊愈率比较无显著性差异（Ｐ>0.05）。两组病例均未发生不良反应。结论：喷昔洛韦乳膏是治疗单纯疱疹的安全有效药物。

Abstract

Objective: To evaluate the efficacy and safety of penciclovir cream against herpes simplex. Methods: Sixty-four patients with herpes simplex were randomly assigned to receive either penciclovir cream or acyclovir cream. Lesions were assessed on days 1

10 and 14. Results: There were statistically significant differences between two groups in terms of time to start escharing

time to complete escharing

time to start shedding and complete shedding (Ｐ<0.05)

there were no statistically significant differences between two groups in the rate of recovery (Ｐ>0.05). There happened to be no adverse effects in two groups. Conclusion: It is indicated that penciclovir cream is well-tolerated and effecitive for the treatment of herpes simplex.

关键词

单纯疱疹喷昔洛韦阿昔洛韦乳膏

Keywords

Herpes simplexPenciclovirAcyclovirCream

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