老年原发性单纯收缩期高血压患者自主神经活性及其昼夜节律变化

邓昌明; 黄晶; 罗开良; 刘东

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老年原发性单纯收缩期高血压患者自主神经活性及其昼夜节律变化

更新时间：2024-01-17

- 老年原发性单纯收缩期高血压患者自主神经活性及其昼夜节律变化
- A study on heart rate variability and its circadian rhythm of elderly patients with isolated systolic hypertension
- 重庆医科大学学报 2002年第4期页码：433-435
- 作者机构：
  
  重庆医科大学第二临床学院心血管内科,重庆,400010
- 作者简介：
- 基金信息：
- DOI：
  中图分类号： R544.1
- 纸质出版日期：2002，
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[1]邓昌明,黄晶,罗开良,刘东.老年原发性单纯收缩期高血压患者自主神经活性及其昼夜节律变化[J].重庆医科大学学报,2002(04):433-435.

A study on heart rate variability and its circadian rhythm of elderly patients with isolated systolic hypertension[J]. Journal of Chongqing Medical University, 2002,(4):433-435.
[1]邓昌明,黄晶,罗开良,刘东.老年原发性单纯收缩期高血压患者自主神经活性及其昼夜节律变化[J].重庆医科大学学报,2002(04):433-435. DOI：

A study on heart rate variability and its circadian rhythm of elderly patients with isolated systolic hypertension[J]. Journal of Chongqing Medical University, 2002,(4):433-435. DOI：

摘要

目的：探讨老年原发性单纯收缩期高血压患者自主神经活性及其昼夜节律变化。方法：对79例老年原发性单纯收缩期高血压患者进行24hHolter监测，然后进行24h及每小时心率变异分析，并与年龄匹配的对照组比较，同时比较高血压伴与不伴左心室肥厚者心率变异及其昼夜节律。结果：老年原发性单纯收缩期高血压患者所有时域指标（SDNN、SDANN、SDNNIDX、rMSSD、pNN50）均降低，而且老年原发性单纯收缩期高血压伴左心室肥厚者rMSSD、pNN50明显低于非肥厚组，昼夜节律减弱。结论：老年原发性单纯收缩期高血压患者自主神经功能受损，平衡失调，而且伴左心室肥厚者迷走神经功能减低更为显著，昼夜节律明显减弱。

Abstract

Objective: To investigate heart rate variability（HRV）and its circadian rhythm of elderly patients with isolated systolic hypertension. Methods: HRV was evaluated by using 24-hour Holter monitoring in 79 isolated systolic hypertensive patients

and compared with age-matched normal controls. Furthermore

HRV and its circadian rhythm were evaluated in two groups with and without left ventricular hypertrophy(LVH). Results: All HRV time domain index were lower among patients than normal controls. As compared with the patients with and without LVH

rMSSD and pNN50 were significantly decreased in patients with LVH. The circadian rhythm was blunted in patients without LVH

but it was absent in patients with LVH. Conclusion: Our results suggest that HRV is decreased in isolated systolic hypertensive patients. And the circadian rhythm in patients with and without LVH is alterd.

关键词

高血压左心室肥厚心率变异昼夜节律

Keywords

Isolated systolic hypertensionleft ventricular hypertrophyheart rate variabilityCircadian rhythm

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