力百汀新剂型治疗慢性支气管炎急性发作的临床研究

卓超; 肖永红; 罗勤东

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力百汀新剂型治疗慢性支气管炎急性发作的临床研究

更新时间：2024-01-17

- 力百汀新剂型治疗慢性支气管炎急性发作的临床研究
- Clinical trial on Augmentin against acute exacerbation of chronic bronchitis (AECB) in adults
- 重庆医科大学学报 2002年第3期页码：339-341
- 作者机构：
  
  1. 重庆医科大学临床学院感染科
  2. 重庆水轮机械厂职工医院,重庆,400016
  3. ,重庆,400063
- 作者简介：
- 基金信息：
- DOI：
  中图分类号： R562.21
- 纸质出版日期：2002，
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[1]卓超,肖永红,罗勤东.力百汀新剂型治疗慢性支气管炎急性发作的临床研究[J].重庆医科大学学报,2002(03):339-341.

ZHUO Chao, et al. Clinical trial on Augmentin against acute exacerbation of chronic bronchitis (AECB) in adults[J]. Journal of Chongqing Medical University, 2002,(3):339-341.
[1]卓超,肖永红,罗勤东.力百汀新剂型治疗慢性支气管炎急性发作的临床研究[J].重庆医科大学学报,2002(03):339-341. DOI：

ZHUO Chao, et al. Clinical trial on Augmentin against acute exacerbation of chronic bronchitis (AECB) in adults[J]. Journal of Chongqing Medical University, 2002,(3):339-341. DOI：

摘要

目的:以力百汀（阿莫西林克拉维酸）新剂型为试验药

头孢呋辛、头孢克洛为对照药

力百汀通过/500/125mg两次口服给药

治疗成年人慢性支气管炎急性发作

评价前者的临床安全性和有效性。方法:随机、单盲、平行法对照研究。结果:三组各完成合格病例例

力百汀组、头孢呋辛组及头孢克洛组的临床有效率分别为、及

细1291.7%83.3%91.7%菌清除率分别为、及

不良反应发生率为、和

三组比较

临床有效率及细菌清除率均无显著性差100%90%71.4%8.3%00异。结论:力百汀新剂型两次口服给药

能安全有效地用于治疗成年慢性支气管炎急性发作。500/125mg

Abstract

Objective:The safty and efficacy of Augmentin (amoxicillin/clavulanic acid 500/125mg) was evaluated through clinical study in treating acute exacerbation of chronic bronchitis. Methods: A randomized-controlled clinical trial on Augmentin

cefuroxime and cefaclor against AECB was designed

Thirty-six patients were enrolled

who were divided into three groups

and each group included twelve patients. Augmentin 625mg Bid×××7d; cefuroxime 250mg Bid7d; cefaclor 250mg Tid7d. Results: The clinical effective rates of augmentin was 91.7%

compared with 83.7% of cefuroxime and 91.7% of cefaclor. The bacterial eradication rate was similar among three groups. Incidence of adverse reactions was 8.3% (1/12) in Augmentin group. Conclusion: The efficacy and safty of Augmentin in treating AECB was reliable.

关键词

力百汀慢性支气管炎急性发作

Keywords

AugmentinAECB

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