Objective: To discover the clinical characteristics of epilepsy in non-ketotic hyperglycaemia and improve the diagnostic accuracy in early stage. Methods: The clinical data of 20 patients with epilepsy in non-ketotic hyperglycaemia were studied retrospectively. Results: Twelve patients had recurrent episodes of seizure when glycaemic control was lost. In eight cases diabetes mellitus was a new diagnosis. Glycemic levels varied from 17.2 to 31.1 mmol/L. Fifteen patients with focal seizures accounted for 75%. Seizure control occurred after insulin treatment
no patients benefited with phenytoin. Conclusion:It is important to increase the knowledgc of epilepsy in non-ketotic hyperglycaemia and early diagnose and insulin treatment are essential in controlling seizures.