Detection of antibody in serum and cerebrospinal fluid of children Japanese encephalitis[J]. Journal of Chongqing Medical University, 2002,(4):456-457.
Detection of antibody in serum and cerebrospinal fluid of children Japanese encephalitis[J]. Journal of Chongqing Medical University, 2002,(4):456-457.DOI:
Objective: To observe the value of detection of JEV-IgM in serum and cerebrospinal fluid for diagnosis of Japanese encephalitis. Methods: JEV-IgM in serum and cerebrospinal fluid were detected by antibody capture method in 182 in-patients with Japanese encephalitis and the relationship between JEV-IgM and duration
age
type of disease was analyzed. Results: The positive rate of JEV-IgM in serum and cerebrospinal fluid were 61.87% and 86.67% respectively with Japanese encephalitis; the latter was significantly higher than the former ( P<0.005); the positive rate of JEV-IgM in serum and cerebrospinal fluid were not markedly different in different duration
age
and type of disease (P>0.05). Conclusion:The determination of JEV-IgM in serum and cerebrospinal fluid with antibody capture method can be used to help the early diagnosis of Japanese encephalitis. The method has best sensitivity and specificity.
关键词
儿童乙型脑炎血清、脑脊液抗JEV-IgM
Keywords
childrenJapanese encephalitisSerum and cerebrospinal fluid JEV-IgM