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1. 重庆医科大学附属第一医院急诊科
2. 重庆医科大学附属第一医院急诊科,重庆,400016
纸质出版日期:2006,
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[1]刘琼,周发春,徐日方.心肺骤停自主循环恢复患者心肌损伤的临床研究[J].重庆医科大学学报,2006(03):430-431+433.
LIU Qiong, et al. Clinical study on myocardial injury in patients with return of spontaneous circulation[J]. Journal of Chongqing Medical University, 2006,(3):430-431.
目的:动态观察心肺骤停患者心肺复苏期间心肌酶谱及血清心肌肌钙蛋白I的动态变化
探讨心肌肌钙蛋白I对心肺骤停自主循环恢复患者心肌损伤的诊断价值。方法:对我院急诊ICU内112例心肺骤停患者实施标准心肺复苏
动态观察心肺骤停即刻和自主循环恢复后患者心肌酶谱及血清心肌肌钙蛋白I的变化。结果:心肺骤停患者在自主循环恢复后1h心肌肌钙蛋白I就明显升高
CK、CK-MB、LDH、AST心肌酶学指标则在复苏后2h开始升高;心肌肌钙蛋白I升高的水平与心肌损伤程度及患者的病死率呈正相关。结论:①心肺骤停自主循环恢复患者存在急性心肌损伤;②心肌肌钙蛋白I血浓度可反映心肌受损严重程度。
Objective: To investigate the changes of serum myocardium enzyme profile and cardiac troponin I(cTnI) in resuscitated patients
and explore the diagnostic value of cTnI on myocardial injury in patients after cardiopulmonary resuscitation.Methods: Standard cardiopulmonary resuscitation was performed in 82 patients with cardia arrest in emergency ICU.Serum myocardium enzymes and cTnI were determined at the point of cardia arrest and after the return of spontaneous circulation(ROSC).Results: The patients′ plasma cTnI levels was elevated significantly 1 hour after ROSC
and CK?CK-MB?LDH and AST level were increased 2 hours after CPR.The level of the elevated cTnI was responsive to the degree of myocardial injury and the fatality ratio of resuscitated patients.Conclusion: Acute myocardial injuries were present in all resuscitated patients.The level of plasma cTnI could reflect the degree of myocardial injury.
心肌损伤心肌酶谱心肌肌钙蛋白I自主循环恢复
Myocardial injurySerum myocardium enzyme profileCardiac troponin IReturn of spontaneous circulation
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