Objective: To investigate the effect of two modes of one-lung ventilation(OLV) on lung lobectomy in pediatric patients.Metheds: Twenty ASA Ⅰ-Ⅱ patients(8 male

12 female) aged 2~14 year

weighing 10~30 kg

and undergoing lung lobectomy were enrolled in this study.The patients were premedicated with intramuscular Sod Luminal 3~5 mg/kg and Atropine 0.01 mg/kg im

30 minutes before induction.Induction was performed with Dorcum 0.1 mg/kg

Fentanyl 5 μg/kg and Vecuronium 0.1 mg/kg

maintained with Vecuronium 70 μg/(kg·h) and Propofol 5mg/(kg·h) iv boluses.Ordinary tracheal tube was inserted into bronchus(14right

6 left) during OLV.First

OLV with volume-control mode maintained 25 min

and then

OLV with pressure-control mode was performed.In first step Vt was set at 8~10 ml/kg and respiratory rate was adjusted to maintain PetCO2 between 30~40 mmHg.In second step the inspiratory pressure was set according to the plateau pressure during step 1

hemodynamics and PaO2 were measured and recorded.Results : During OLV with pressure-control mode PaO2 was significantly increased

as compared with that during volume-control mode(P<0.05).Conclusion : PaO2 is higher in OLV-PCV group than that in OLV-VCV group.