CHEN Mingfang. Clinical significance of a-L-Fucosidase activity in the diagnosisof primary hepatic carcinoma[J]. Journal of Chongqing Medical University, 2006,(3):440-442.
CHEN Mingfang. Clinical significance of a-L-Fucosidase activity in the diagnosisof primary hepatic carcinoma[J]. Journal of Chongqing Medical University, 2006,(3):440-442.DOI:
Objective: To analyse the clinical significance of a-L-Fucosidase(AFU) in the diagnosis of primary hepatic carcinoma(PHC).Methods: The activity of serum AFU was measured in 33 patients with PHC
42 patients with cirrhosis
37 patients whit hepatitis
10 patients with secondary liver cancer
37 patients with other malignant tumors and 80 normal persons.The differences of the level of AFU between the groups were compared.Results: The mean serum AFU activity was significantly higher in patients with PHC(41.2±14.1 U/L) than that in normal persons(20.5±7.2U/L)
secondary liver cancer(22.2±13.6 U/L)
other kinds of malignant tumors(22.0±7.1 U/L)
P<0.01 and hepatocirrhosis(25.5±13.0 U/L)
0.01<P<0.05.Conclusion:AFU is a specific maker in the PHC and can be used to diagnosis early PHC.