XIONG Yin, et al. Study on the effects of exogenous quinolinic acid on acute and subacute inflammation in animal models[J]. Journal of Chongqing Medical University, 2006,(6):845-847.
XIONG Yin, et al. Study on the effects of exogenous quinolinic acid on acute and subacute inflammation in animal models[J]. Journal of Chongqing Medical University, 2006,(6):845-847.DOI:
Objective: To investigate the anti-inflammatory effects of quinolinic acid.Methods: Kunming mouse or Wistar rat was selected to proceed experiments.Influences of quinolinic acid on tumidness caused by dimethylbenzene in mouse’s ear
on wandering of rat WBC caused by CMC injection
on increasement of mouse capillary vessel permeability caused by acetic acid
on granuloma in rat’s armpit caused by tampon and phagocytosis of mouse were investigated
respectively.Results: Obvious suppression of all the inflammatory models was observed.Conclusion:Exogenous quinolinic acid is endowed with quite evident anti-inflammatory effects on either acute or subacute animal models with somewhat immunological inhibition.