An tentative radiological and basical studies of preventing the constriction after the laminectomy by using the nano-hydroxyapatite/polyamide-66 composite material artificial vertebral lamina
XIAO Zhibo, et al. An tentative radiological and basical studies of preventing the constriction after the laminectomy by using the nano-hydroxyapatite/polyamide-66 composite material artificial vertebral lamina[J]. Journal of Chongqing Medical University, 2006,(4):489-493.
XIAO Zhibo, et al. An tentative radiological and basical studies of preventing the constriction after the laminectomy by using the nano-hydroxyapatite/polyamide-66 composite material artificial vertebral lamina[J]. Journal of Chongqing Medical University, 2006,(4):489-493.DOI:
Objective: To discuss the radiological evaluation after the experiment implanted artificial vertebral lamina made from n-HA/PA66 into the defect of vertebral lamina
in order to evaluate its value in preventing the complication of postlaminectomy.Methods:22 male dogs aged one year were classified randomly into three groups: the experimental group(13 dogs)and the control group(9 dogs).The specimens were examined by the methods of plain roentgenography
MRI and histology.Results:The X-ray: in the experimental group
it was becoming cloudy around the operative area in the 8th week;till 24th week
the density of the operative area was the same with the density of bone.The histology: in the experimental group
from the 8th week
there were many cartilage cells and lamellar bone observed.While in the control group
it was just fibrous layer forming.MRI:the reconstructed segment after the laminoplasty was detected clearly by MRI
which coincided with the histology.Compared with the control segment
the numbers of the area of vertebral canal and the sagital axis were significantly different(P<0.05).Conclusion: The experimental results show that n-HA/PA66 composite material not only has the attribute of good biocompatibility
but also can effectively prevent the scar formation and adhesion.
which can be detected by the X-ray and MRI exactly.