Objective:To analyses distribution and resistant profile of acquired infections of acinetobacter baumanii.Methods:Distribution and the resistant patterns of acquired infections of acinetobacter baumanii in our hospital were analysed by a retrospective analysis from the year 2003~2005.All of the isolates were tested by Kirby-Bauer susceptibility

and the antibiotic resistance was judged according to NCCLS standard.Results:The isolation rate of Acinetobacter baumannii was the higher in vena pipe

sputum

secretion and bile

the isolation rate was 11.5%~37.5%respectively.Primary acquired infections were Acinetobacter baumannii in department of breathe

burn

neurosurgery

heart internal medicine

transplantation

chest surgery and intensive care units.The bacterial resis-tancet rate to common antimicrobial agents increased year by year.There sistance rate s of Acinetobacter baumannii to antibiotics such as Cefop-erazone

Ampicillin

Ceftriaxone

Cefuroxime

Amoxicillin/Clavulanic Acid were over 50 % every year respectively.Levofloxacin

Meraopenem

Imipenem

Cefopera-zone/Sulbactam

Ampicillin/Sulbactam and Piperacillin/Tazobactam all had antisepsis activity to Acinetobacter baumannii relatively.Conclusion:The infection rate and the antibiotics rate of hospital acquired infections of Acinetobacter baumannii was yearly increase

resistance to anti-microbial agents have the characteristics of high prevalence.Its necessary to strengthen the clinic monitoring and select reasonable antibiotic in order to improve curative effect and delay bacteria of resistance to antimicrobial agents.