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1. 重庆医科大学附属第二医院放射介入中心
2. 重庆医科大学附属第二医院放射介入中心,重庆,400010
纸质出版日期:2007,
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[1]罗小平,谢微波.超选择性肿瘤滋养动脉插管化疗栓塞在肺肿瘤治疗中的价值(附90例报告)[J].重庆医科大学学报,2007(08):862-865+879.
LUO Xiaoping, et al. Values of superselective transcatheter arterial chemoemboliazation (TACE) for feeding artery of the lung neoplasm[J]. Journal of Chongqing Medical University, 2007,(8):862-865.
目的:评价支气管肺癌及肺富血转移性瘤的肿瘤滋养动脉超选择性化疗栓塞的安全性、技术成功率与疗效。材料与方法:在日本岛津1250MA CCD数字减影X光机的引导下
使用4F RH或4F YASHIRO超滑导管及3F超滑微导管实施超选择性肿瘤滋养动脉插管
以超液态碘油及2~3种化疗药物(依肿瘤类型而定)对临床及(或)病理证实的原发性支气管肺癌、肺富血供性转移瘤灶实施完全性化疗栓塞
重复治疗间隔时间4~6周
术后随访观察临床症状的变化、肿瘤的影像学改变、生存率等。结果:88例肺癌与肺富血性转移瘤成功实施超选择性肿瘤滋养动脉插管、栓塞
技术操作成功率97.8%(88/90)
无脊髓损伤发生。经过1~3次治疗后
患者临床症状明显改善96.7%(87/90);肿块明显缩小91.1%(82/90)
肿块缩小6%(5/90)
肿块无明显变化3.3%(3/90)。术后6个月、1年、2年、3年生存率分别为98.9%(89/90)、93.3%(84/90)、83.3%(75/90)、53.3%(48/90)。结论:肺富血性肿瘤之瘤灶滋养动脉超选择性插管化疗栓塞的技术操作成功率高、并发症发生率低
其疗效明显优于支气管动脉灌注化疗。
Objective:To evaluate the safety
technical success rate
and effectiveness of transcatheter superselective arterial chemoembolization(TACE)for unresectable lung cancer and the metastases tumor with rich blood feeding in lung.Methods:Using Japan Shimadzu 1250Ma CCD DSA X machine
4F RH or 4F YASHIRO catheter and 3F SP microcatheter were employed in superselective chemoembolization for feeding artery of lung cancer and the metastases tumor with rich blood feeding in lung with lipiodol and 2~3 species chemodrug.The period of repetitive treatment was 4~6weeks.After treatment
the change of the symptoms
images of neoplasm and the survival rates were observed.Results:Transcatheterization and embolization were successfully completed in 88 out of 90 cases.Technical success rate was 97.8% without spinal damage occuring.After 2~3 time treatment
the symptoms of the patients obviously improved in 87cases(96.7%);neoplasm notable shrank in 82 cases(91.1%)
partly shrank in 5 cases(6%)
not shrinking in 3 cases(3.3%).The survival rate respectively at 6 months
12 months
24 months
36 months were 98.8%(89/90)
93.3%(84/90)
83.3%(75/90)and 53.3%(48/90).Conclusions:The technical success rate at Superselective transcatheter arterial chemoembolization for feeding artery of the neoplasm that rich blood fed in lung is high.Complications rate is lower.Its effectiveness is more notable than bronchial artery chemodrug infusion.
肺恶性肿瘤滋养动脉超选择性化疗栓塞
Lung neoplasmFed arterySuper selectivechemoembolization
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