Objective:To elucidate the clinical features of acute disseminated encephalomyelitis

as well as its diagnosis and treatment.Methods:The general clinical manifestations

lesion locations

the results of cardinal ancillary investigations

and treatment as well as prognosis of 86 ADEM patients were comprehensively analyzed.Results:ADEM mainly occurred in children

young and middle-aged people.Their onsets were relatively acute.The upper respiratory tract infection and vaccination

measles

german measles

chickenpox

mumps

scarlet fever were the main predisposing factors.The immunoglobin in CSF increased.Spinal cord

cerebellum

cerebral medullary substance and brain stem were often involved.Imaging investigations

electrophysiology and immunology were helpful for diagnosis.The administration of glucocorticoid was effective.Conclusion:In addition to clinical features

neuroelectrophysiology

CSF immunology and imaging investigations altogether greatly aid clinical definite diagnosis.It is important to treat the patients in time and properly for the better prognosis.