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1. 深圳市人民医院(暨南大学医学院附二院)骨科
2. 中山医科大学附属第二医院骨科
纸质出版日期:2007,
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[1]卢小虎,刘尚礼,段贤斌,卢红,刘婕.犬髋关节一过性滑膜炎关节内压的动物实验研究[J].重庆医科大学学报,2007(06):643-644+656.
LU Xiaohu, et al. Animal experimental study on the intra-articular pressure change children with synoyitis of hip[J]. Journal of Chongqing Medical University, 2007,(6):643-644.
目的:在幼犬髋关节腔内注入2‰去甲肾上腺素
诱导髋关节一过性滑膜炎
动态观察髋关节内压的变化
探讨关节内压的变化对髋关节一过性滑膜炎的影响。方法:48只2~3月大小的幼犬
随机分为12组
每组4只
分别在髋关节内注入2‰的去甲肾上腺素
用99m锝-亚甲基二磷酸盐(99m TC-MDP)三相骨显像
在不同时间测定关节内压变化
同时观察股骨头局部循环血流、病理组织学变化、X-Ray照片检查。结果:去甲肾上腺素注入关节腔内后产生滑膜炎
关节内压增高
随着炎症消退而恢复正常
但最高不超过20mmHg
股骨头出现一过性缺血
未出现股骨头坏死。结论:髋关节一过性滑膜炎时
滑膜炎症导致关节内压增高
随着炎症消退关节内压恢复正常
关节内压变化影响股骨头供血情况
引起股骨头一过性缺血。
Objective:To dynamically observe the change of intra-articular pressure of the hip by means of injecting 2‰Noradrenaline(NA)into the hip joint cavity
to study the effects of intra-articular pressure change on transient synovitis of hip(TSH).Methods:Fourty-eight dogs aged 2~3 months had been randomly divided into 12 groups
with four in each group All were injected 2‰NA into the hip joint an four assessments had been done.①The intra-articular pressure of hip was determined at different times.②99m TC-MDP triphasic imaging was used to observe the local blood supply of femoral head.③Pathological changes were observed to understand the disease course.④X-ray was adopted to exmine the hip.Result:Noradrenaline induced transient synovitis of hip
and synovitis resulted in the increase of intra-articular pressure of hip which was over 20mmHg and lowered to be normal with the inflammation fading away.Transient blood insufficiency was observed in femoral head
but with no putrescence.Conclusion:In transient synovitis of hip
synovitis resulted in the change of intra-articular pressure hip
which changed to be normal as the inflammation faded away;and the intra-articular pressure change would influence the blood supply in femoral head
and could canse transient blood insufficiency.
髋关节关节内压滑膜炎
HipIntra-articular pressureSnovitis
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